| Gene Information | |
|---|---|
| Gene Name | CENPP |
| Organism | Homo sapiens (Human) |
| Gene Length | 288 |
| Protein Names | Centromere protein P (CENP-P) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000188312 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6IPU0 |
| Gene Card | CENPP |
| Uniprot ID | Q6IPU0 |
| Pfam | PF13096 |
| In ASD | no |
| Allosteric Prediction | no (-0.999961329) |
| Ortholog in Animals | Alpaca_ CENPP ( ortholog_one2one ) Dog_ CENPP ( ortholog_one2one ) GuineaPig_ CENPP ( ortholog_one2one ) Macaque_ CENPP ( ortholog_one2one ) Mouse_ Cenpp ( ortholog_one2one ) Pig_ CENPP ( ortholog_one2one ) Rat_ Cenpp ( ortholog_one2one ) Rabbit_ CENPP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.094444(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7PB8 (X-ray 3.68A ) 7PKN (EM 3.20A ) 7QOO (EM 4.60A ) 7R5S (EM 2.83A ) 7R5V (EM 4.55A ) 7YWX (EM 12.00A ) 7YYH (EM 8.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16622420}. Chromosome, centromere {ECO:0000269|PubMed:16622420}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex. |
| Mouse PG classification | NA |
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