| Gene Information | |
|---|---|
| Gene Name | GPX3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 226 |
| Protein Names | Glutathione peroxidase 3 (GPx-3) (GSHPx-3) (EC 1.11.1.9) (Extracellular glutathione peroxidase) (Plasma glutathione peroxidase) (GPx-P) (GSHPx-P) |
| Target Name | glutathione peroxidase 3 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000211445 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | GPX3 |
| Uniprot ID | P22352 |
| Pfam | PF00255 |
| In ASD | no |
| Allosteric Prediction | no (-0.227109527) |
| Ortholog in Animals | Alpaca_ GPX3 ( ortholog_one2one ) Dog_ GPX3 ( ortholog_one2one ) GuineaPig_ GPX3 ( ortholog_one2one ) Macaque_ GPX3 ( ortholog_one2one ) Mouse_ Gpx3 ( ortholog_one2one ) Pig_ GPX3 ( ortholog_one2one ) |
| Ohnologs | GPX6 |
| Paralogs | GPX4, GPX7, GPX8, GPX1, GPX5, GPX2, GPX6 |
| Tissue | breast, heart, kidney, left.atrium, left.ventricle, vagina |
| Tissue Specificity | Secreted in plasma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2R37 (X-ray 1.85A ) |
| DBSNP | rs8177445 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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