| Gene Information | |
|---|---|
| Gene Name | KIAA0709 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1479 |
| Protein Names | C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UBG0 |
| Gene Card | MRC2 |
| Uniprot ID | Q9UBG0 |
| Pfam | PF00040; PF00059 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous with low expression in brain, placenta, lung, kidney, pancreas, spleen, thymus and colon. Expressed in endothelial cells, fibroblasts and macrophages. Highly expressed in fetal lung and kidney. {ECO:0000269|PubMed:10683150, ECO:0000269|PubMed:8702911}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5AO5 (X-ray 2.48A ) 5AO6 (X-ray 3.36A ) 5E4K (X-ray 2.58A ) 5E4L (X-ray 2.44A ) 5EW6 (X-ray 2.29A ) |
| DBSNP | rs2014055 rs2429387 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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