| Gene Information | |
|---|---|
| Gene Name | ETAA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 926 |
| Protein Names | Ewing's tumor-associated antigen 1 (Ewing's tumor-associated antigen 16) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000143971 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NY74 |
| Gene Card | ETAA1 |
| Uniprot ID | Q9NY74 |
| Pfam | PF15350 |
| In ASD | no |
| Allosteric Prediction | no (-1.5321636) |
| Ortholog in Animals | Alpaca_ ETAA1 ( ortholog_one2one ) Dog_ ETAA1 ( ortholog_one2one ) GuineaPig_ ETAA1 ( ortholog_one2one ) Macaque_ ETAA1 ( ortholog_one2one ) Mouse_ Etaa1 ( ortholog_one2one ) Pig_ ETAA1 ( ortholog_one2one ) Rat_ Etaa1l1 ( ortholog_one2one ) Rabbit_ ETAA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines. {ECO:0000269|PubMed:16003559}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13036061 rs3770657 rs3770656 rs3770655 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:27601467, ECO:0000269|PubMed:27723717, ECO:0000269|PubMed:27723720}. Note=Localizes at sites of DNA damage following replication stress (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex (PubMed:27601467, PubMed:27723720). {ECO:0000269|PubMed:27601467, ECO:0000269|PubMed:27723717, ECO:0000269|PubMed:27723720}. |
| Mouse PG classification | NA |
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