| Gene Information | |
|---|---|
| Gene Name | KIAA0679 |
| Organism | Homo sapiens (Human) |
| Gene Length | 916 |
| Protein Names | Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (NCOAT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O60502 |
| Gene Card | OGA |
| Uniprot ID | O60502 |
| Pfam | PF07555 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Shows highest expression in the brain, placenta and pancreas. {ECO:0000269|PubMed:11148210, ECO:0000269|PubMed:11341771}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YDQ (X-ray 2.60A ) 5M7R (X-ray 2.35A ) 5M7S (X-ray 2.40A ) 5M7T (X-ray 2.60A ) 5M7U (X-ray 2.30A ) 5TKE (X-ray 2.48A ) 5UHK (X-ray 2.97A ) 5UHL (X-ray 3.14A ) 5UHO (X-ray 3.21A ) 5UHP (X-ray 2.79A ) 5UN8 (X-ray 2.13A ) 5UN9 (X-ray 2.50A ) 5VVO (X-ray 2.60A ) 5VVT (X-ray 2.80A ) 5VVU (X-ray 2.70A ) 5VVV (X-ray 2.80A ) 5VVX (X-ray 2.90A ) 6HKI (X-ray 3.30A ) 6PM9 (X-ray 2.86A ) 7OU6 (X-ray 2.41A ) |
| DBSNP | rs3740421 rs17853930 |
| Subcellular location [CC] | [Isoform 3]: Nucleus {ECO:0000269|PubMed:11341771}.; [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:11148210, ECO:0000269|PubMed:11341771, ECO:0000269|PubMed:11788610}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |