| Gene Information | |
|---|---|
| Gene Name | IGFR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 310 |
| Protein Names | Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P31994 |
| Gene Card | FCGR2B |
| Uniprot ID | P31994 |
| Pfam | PF13895 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2FCB (X-ray 1.74A ) 3WJJ (X-ray 2.60A ) 5OCC (X-ray 2.50A ) |
| DBSNP | rs5017567 rs1050499 rs1050501 rs148534844 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |