| Gene Information | |
|---|---|
| Gene Name | RNF40 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1001 |
| Protein Names | E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000103549 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75150 |
| Gene Card | RNF40 |
| Uniprot ID | O75150 |
| Pfam | PF00097 |
| In ASD | no |
| Allosteric Prediction | no (-0.161901395) |
| Ortholog in Animals | Alpaca_ RNF40 ( ortholog_one2one ) Dog_ RNF40 ( ortholog_one2one ) GuineaPig_ RNF40 ( ortholog_one2one ) Macaque_ RNF40 ( ortholog_one2one ) Mouse_ Rnf40 ( ortholog_one2one ) Pig_ RNF40 ( ortholog_one2one ) Rat_ Rnf40 ( ortholog_one2one ) Rabbit_ RNF40 ( ortholog_one2one ) |
| Ohnologs | RNF20 |
| Paralogs | RNF20 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Expressed at higher level in testis, heart and pancreas, while it is only weakly expressed in lung, skeletal muscle and small intestine. {ECO:0000269|PubMed:10944455}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.021053(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11556801 rs7195142 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10944455}. |
| Mouse PG classification | NA |
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