| Gene Information | |
|---|---|
| Gene Name | KIAA0474 |
| Organism | Homo sapiens (Human) |
| Gene Length | 663 |
| Protein Names | Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P47736 |
| Gene Card | RAP1GAP |
| Uniprot ID | P47736 |
| Pfam | PF02188; PF02145 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues. {ECO:0000269|PubMed:9346962}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1SRQ (X-ray 2.90A ) 3BRW (X-ray 3.40A ) |
| DBSNP | rs2275363 rs147394161 |
| Subcellular location [CC] | Golgi apparatus membrane; Peripheral membrane protein. |
| Mouse PG classification | NA |
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