| Gene Information | |
|---|---|
| Gene Name | ATG2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1938 |
| Protein Names | Autophagy-related protein 2 homolog A |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000110046 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q2TAZ0 |
| Gene Card | ATG2A |
| Uniprot ID | Q2TAZ0 |
| Pfam | PF09333; PF12624 |
| In ASD | no |
| Allosteric Prediction | no (-1.140760355) |
| Ortholog in Animals | Alpaca_ ATG2A ( ortholog_one2one ) Dog_ ATG2A ( ortholog_one2one ) GuineaPig_ ATG2A ( ortholog_one2one ) Macaque_ ATG2A ( ortholog_one2one ) Mouse_ Atg2a ( ortholog_one2one ) Pig_ ATG2A ( ortholog_one2one ) Rat_ Atg2a ( ortholog_one2one ) Rabbit_ ATG2A ( ortholog_one2one ) |
| Ohnologs | ATG2B |
| Paralogs | ATG2B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.133333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6KLR (X-ray 2.21A ) |
| DBSNP | rs12293826 rs35115827 rs60711419 rs2285347 rs656195 rs11827140 |
| Subcellular location [CC] | Preautophagosomal structure membrane {ECO:0000269|PubMed:30952800}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96BY7}. Lipid droplet {ECO:0000250|UniProtKB:Q96BY7}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:30952800}; Peripheral membrane protein {ECO:0000250|UniProtKB:P53855}. Note=Localizes to endoplasmic reticulum-autophagosome contact sites. {ECO:0000269|PubMed:30952800}. |
| Mouse PG classification | NA |
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