Gene Information | |
---|---|
Gene Name | KIAA0367 |
Organism | Homo sapiens (Human) |
Gene Length | 3088 |
Protein Names | Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1) |
Target Name | NA |
Target Type | NA |
Gene Age | NA |
Evolutionary Stage | NA |
AlphaFoldDB | NA |
Gene Card | PRUNE2 |
Uniprot ID | Q8WUY3 |
Pfam | PF12496; PF13716; PF02833 |
In ASD | no |
Allosteric Prediction | NA |
Ortholog in Animals | NA |
Ohnologs | NA |
Paralogs | NA |
Tissue | NA |
Tissue Specificity | A high level of expression seen in the nervous system (brain, cerebellum and spinal cord) as well as adrenal gland. Expressed at high levels in noneuroblastoma, rhabdomyosarcoma, melanoma and some osteosarcoma cell lines, whereas at only low levels in cancer cell lines of liver, breast, thyroid and colon. Expression is significantly higher in favorable tumors than aggressive ones. {ECO:0000269|PubMed:16288218}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
|
PDB | NA |
DBSNP | rs375315668 |
Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16288218}. |
Mouse PG classification | NA |
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