| Gene Information | |
|---|---|
| Gene Name | KIAA0333 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2240 |
| Protein Names | Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BTC0 |
| Gene Card | DIDO1 |
| Uniprot ID | Q9BTC0 |
| Pfam | PF00628; PF07744; PF07500 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);0.042553(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2M3H (NMR - ) 4L7X (X-ray 1.35A ) |
| DBSNP | rs6090161 rs6090160 rs1883848 rs1883847 rs750077 rs6011441 rs41282984 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00651}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:23831028}. Note=Translocates to the nucleus after pro-apoptotic stimuli (By similarity). Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis. {ECO:0000250}. |
| Mouse PG classification | NA |
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