| Gene Information | |
|---|---|
| Gene Name | PANK4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 773 |
| Protein Names | 4'-phosphopantetheine phosphatase (EC 3.1.3.-) (Inactive pantothenic acid kinase 4) (hPanK4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000157881 ) 3 ( ENSG00000273494 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NVE7 |
| Gene Card | PANK4 |
| Uniprot ID | Q9NVE7 |
| Pfam | PF01937; PF03630 |
| In ASD | no |
| Allosteric Prediction | yes (0.266006038) |
| Ortholog in Animals | Alpaca_ PANK4 ( ortholog_one2many ) Dog_ PANK4 ( ortholog_one2one ) GuineaPig_ PANK4 ( ortholog_one2one ) Macaque_ PANK4 ( ortholog_one2one ) Mouse_ Pank4 ( ortholog_one2one ) Pig_ PANK4 ( ortholog_one2one ) Rat_ Pank4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PANK2, PANK3, PANK1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with high expression in the muscle (PubMed:11479594). Expressed in the retina and lens epithelium, mainly in ganglion cell layer, outer plexiform layer and retinal pigment layer (at protein level) (PubMed:30585370). {ECO:0000269|PubMed:11479594, ECO:0000269|PubMed:30585370}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs966358882 rs7535528 rs2494620 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q923S8}. |
| Mouse PG classification | NA |
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