| Gene Information | |
|---|---|
| Gene Name | SGSM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 749 |
| Protein Names | Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000100359 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96HU1 |
| Gene Card | SGSM3 |
| Uniprot ID | Q96HU1 |
| Pfam | PF00566; PF02759; PF00018 |
| In ASD | no |
| Allosteric Prediction | no (-0.794483575) |
| Ortholog in Animals | Alpaca_ SGSM3 ( ortholog_one2one ) Dog_ SGSM3 ( ortholog_one2one ) GuineaPig_ SGSM3 ( ortholog_one2one ) Macaque_ SGSM3 ( ortholog_one2one ) Mouse_ Sgsm3 ( ortholog_one2one ) Pig_ SGSM3 ( ortholog_one2one ) Rat_ Sgsm3 ( ortholog_one2one ) Rabbit_ SGSM3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TBC1D3C, TBC1D3D, TBC1D3, TBC1D3G, TBC1D3B, TBC1D3F, TBC1D3I, TBC1D3E, TBC1D3L, TBC1D3H, TBC1D3K, TBC1D8, TBC1D14, TBC1D10A, SGSM1, TBC1D8B, TBC1D2B, TBC1D10B, RABGAP1, TBC1D17, TBC1D9B, TBC1D25, TBC1D30, TBC1D26, TBC1D28, TBC1D22A, USP6NL, TBC1D9, RABGAP1L, TBC1D2, TBC1D13, TBC1D12, SGSM2, TBC1D4, GRTP1, EVI5, EVI5L, TBC1D15, TBC1D16, TBCK, TBC1D22B, TBC1D5, TBC1D1, TBC1D10C, TBC1D21 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:17509819}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs9611338 rs34243479 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15849434}. |
| Mouse PG classification | NA |
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