| Gene Information | |
|---|---|
| Gene Name | KIAA0255 |
| Organism | Homo sapiens (Human) |
| Gene Length | 642 |
| Protein Names | Transmembrane 9 superfamily member 4 (Tumor cannibalism associated protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q92544 |
| Gene Card | TM9SF4 |
| Uniprot ID | Q92544 |
| Pfam | PF02990 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in metastatic melanoma cells whereas it is undetectable in primary melanoma cells, healthy skin tissues and peripheral blood lymphocytes. Expressed in CD34(+) hematopoietic progenitor cells and during monocyte and granulocyte differentiation. Overexpressed in acute myeloid leukemia, in particular in those displaying granulocytic differentiation (at protein level). {ECO:0000269|PubMed:19893578, ECO:0000269|PubMed:25961573}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus {ECO:0000269|PubMed:25999474}. Early endosome {ECO:0000269|PubMed:19893578}. |
| Mouse PG classification | NA |
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