| Gene Information | |
|---|---|
| Gene Name | ZC3HAV1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 902 |
| Protein Names | Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Inactive Poly [ADP-ribose] polymerase 13) (PARP13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000105939 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7Z2W4 |
| Gene Card | ZC3HAV1 |
| Uniprot ID | Q7Z2W4 |
| Pfam | PF18606; PF00644; PF02825; PF18633 |
| In ASD | no |
| Allosteric Prediction | yes (0.143627879) |
| Ortholog in Animals | Alpaca_ ZC3HAV1 ( ortholog_one2one ) Dog_ ZC3HAV1 ( ortholog_one2one ) GuineaPig_ ZC3HAV1 ( ortholog_one2one ) Macaque_ ZC3HAV1 ( ortholog_one2one ) Mouse_ Zc3hav1 ( ortholog_one2one ) Pig_ ZC3HAV1 ( ortholog_one2one ) Rat_ Zc3hav1 ( ortholog_one2one ) Rabbit_ ZC3HAV1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZC3HAV1L, PARP14, PARP12, PARP9, PARP10, PARP11, PARP15, TIPARP |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2X5Y (X-ray 1.05A ) 4X52 (X-ray 2.08A ) 6UEI (X-ray 2.51A ) 6UEJ (X-ray 2.21A ) 7KZH (X-ray 2.49A ) 7TGQ (X-ray 2.00A ) |
| DBSNP | rs2236426 rs2297241 rs2297236 rs3735007 |
| Subcellular location [CC] | [Isoform 1]: Cytoplasm {ECO:0000250|UniProtKB:Q8K3Y6}. Nucleus {ECO:0000250|UniProtKB:Q8K3Y6}. Note=Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. {ECO:0000250|UniProtKB:Q8K3Y6}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:21102435}. |
| Mouse PG classification | NA |
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