| Gene Information | |
|---|---|
| Gene Name | SLC2A12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 617 |
| Protein Names | Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000146411 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8TD20 |
| Gene Card | SLC2A12 |
| Uniprot ID | Q8TD20 |
| Pfam | PF00083 |
| In ASD | no |
| Allosteric Prediction | no (-0.317080571) |
| Ortholog in Animals | Alpaca_ SLC2A12 ( ortholog_one2one ) Dog_ SLC2A12 ( ortholog_one2one ) GuineaPig_ SLC2A12 ( ortholog_one2one ) Macaque_ SLC2A12 ( ortholog_one2one ) Mouse_ Slc2a12 ( ortholog_one2one ) Pig_ SLC2A12 ( ortholog_one2one ) Rat_ Slc2a12 ( ortholog_one2one ) Rabbit_ SLC2A12 ( ortholog_one2one ) |
| Ohnologs | SLC2A10 |
| Paralogs | SLC2A8, SLC2A7, SLC2A6, SLC2A5, SLC2A11, SLC2A2, SLC2A1, SLC2A4, SLC2A3, SLC2A14, SLC2A13, SLC2A9, SLC2A10 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain, placenta and kidney. {ECO:0000269|PubMed:11832379}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q8BFW9}; Multi-pass membrane protein {ECO:0000255}. Endomembrane system {ECO:0000250|UniProtKB:Q5J316}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:11832379}. Note=Localizes primarily perinuclear region in the absence of insulin. {ECO:0000269|PubMed:11832379}. |
| Mouse PG classification | NA |
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