| Gene Information | |
|---|---|
| Gene Name | MGAT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 445 |
| Protein Names | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I) |
| Target Name | alpha-1,3-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000131446 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P26572 |
| Gene Card | MGAT1 |
| Uniprot ID | P26572 |
| Pfam | PF03071 |
| In ASD | no |
| Allosteric Prediction | yes (0.099705503) |
| Ortholog in Animals | Alpaca_ MGAT1 ( ortholog_one2one ) GuineaPig_ MGAT1 ( ortholog_one2one ) Macaque_ MGAT1 ( ortholog_one2one ) Mouse_ Mgat1 ( ortholog_one2one ) Pig_ MGAT1 ( ortholog_one2one ) Rat_ Mgat1 ( ortholog_one2one ) Rabbit_ MGAT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | POMGNT1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7726005 rs634501 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:20378551}; Single-pass type II membrane protein {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:30983867}. Note=Co-localizes with BRI3 isoform 1 at the perinuclear region. {ECO:0000269|PubMed:30983867}. |
| Mouse PG classification | NA |
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