Gene Information
Gene NameKIAA0321
OrganismHomo sapiens (Human)
Gene Length2539
Protein NamesZinc finger FYVE domain-containing protein 26 (FYVE domain-containing centrosomal protein) (FYVE-CENT) (Spastizin)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ68DK2
Gene CardZFYVE26
Uniprot IDQ68DK2
PfamPF01363
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityStrongest expression in the adrenal gland, bone marrow, adult brain, fetal brain, lung, placenta, prostate, skeletal muscle, testis, thymus, and retina. Intermediate levels are detected in other structures, including the spinal cord. {ECO:0000269|PubMed:18394578}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34059852  rs17192170  rs35471427  rs7156206  rs3742885  rs3742884  rs2235967  rs3742883  rs200595749  rs34373049 
Subcellular location [CC]Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20208530}. Midbody {ECO:0000269|PubMed:20208530}. Note=Localizes to the centrosome during all stages of the cell cycle. Recruited to the midbody during cytokinesis by KIF13A.
Mouse PG classificationNA
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