| Gene Information | |
|---|---|
| Gene Name | KDM6B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1643 |
| Protein Names | Lysine-specific demethylase 6B (EC 1.14.11.68) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3) (Lysine demethylase 6B) ([histone H3]-trimethyl-L-lysine(27) demethylase 6B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000132510 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O15054 |
| Gene Card | KDM6B |
| Uniprot ID | O15054 |
| Pfam | PF02373 |
| In ASD | no |
| Allosteric Prediction | yes (0.360337394) |
| Ortholog in Animals | Alpaca_ KDM6B ( ortholog_one2one ) Dog_ KDM6B ( ortholog_one2one ) GuineaPig_ KDM6B ( ortholog_one2one ) Macaque_ KDM6B ( ortholog_one2one ) Mouse_ Kdm6b ( ortholog_one2one ) Pig_ KDM6B ( ortholog_one2one ) Rat_ Kdm6b ( ortholog_one2one ) Rabbit_ KDM6B ( ortholog_one2one ) |
| Ohnologs | UTY |
| Paralogs | KDM6A, UTY |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2XUE (X-ray 2.00A ) 2XXZ (X-ray 1.80A ) 4ASK (X-ray 1.86A ) 5FP3 (X-ray 2.05A ) 5OY3 (X-ray 2.14A ) 6F6D (X-ray 1.82A ) |
| DBSNP | rs60738318 rs2270516 rs1567802147 rs1567802439 |
| Subcellular location [CC] | Nucleus {ECO:0000305|PubMed:17825402}. |
| Mouse PG classification | NA |
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