| Gene Information | |
|---|---|
| Gene Name | KDM6A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1401 |
| Protein Names | Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000147050 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O15550 |
| Gene Card | KDM6A |
| Uniprot ID | O15550 |
| Pfam | PF02373; PF13181 |
| In ASD | no |
| Allosteric Prediction | yes (0.013481771) |
| Ortholog in Animals | Alpaca_ KDM6A ( ortholog_one2one ) Dog_ KDM6A ( ortholog_one2one ) GuineaPig_ KDM6A ( ortholog_one2one ) Macaque_ KDM6A ( ortholog_one2one ) Mouse_ Kdm6a ( ortholog_one2one ) Pig_ KDM6A ( ortholog_one2one ) Rat_ Kdm6a ( ortholog_one2one ) Rabbit_ KDM6A ( ortholog_one2one ) |
| Ohnologs | UTY |
| Paralogs | UTY, KDM6B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3AVR (X-ray 1.80A ) 3AVS (X-ray 1.85A ) 6FUK (X-ray 2.00A ) 6FUL (X-ray 1.65A ) |
| DBSNP | rs6529 rs6530 rs34922269 rs2230018 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | LPG |
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