Gene Information
Gene NameKDM1B
OrganismHomo sapiens (Human)
Gene Length822
Protein NamesLysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B)
Target Namelysine-specific histone demethylase 1b
Target TypePatented-recorded target
Gene Age645 ( ENSG00000165097 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ8NB78
Gene CardKDM1B
Uniprot IDQ8NB78
PfamPF01593; PF04433; PF07496
In ASDno
Allosteric Predictionno (-0.460795864)
Ortholog in AnimalsAlpaca_ KDM1B ( ortholog_one2one )
Dog_ KDM1B ( ortholog_one2one )
GuineaPig_ KDM1B ( ortholog_one2one )
Macaque_ KDM1B ( ortholog_one2one )
Mouse_ Kdm1b ( ortholog_one2one )
Pig_ KDM1B ( ortholog_one2one )
Rat_ Kdm1b ( ortholog_one2one )
Rabbit_ KDM1B ( ortholog_one2one )
OhnologsNA
ParalogsKDM1A, MAOA, SMOX, PPOX, PAOX, MAOB, IL4I1
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.000730(Chimpanzee);0.018150(Mouse);0.001000(Rat);0.025000(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4FWE  (X-ray  2.13A  )  4FWF  (X-ray  2.70A  )  4FWJ  (X-ray  2.90A  )  4GU0  (X-ray  3.10A  )  4GU1  (X-ray  2.94A  )  4GUR  (X-ray  2.51A  )  4GUS  (X-ray  2.23A  )  4GUT  (X-ray  2.00A  )  4GUU  (X-ray  2.30A  )  4HSU  (X-ray  1.99A  )  6R1U  (EM  4.36A  )  6R25  (EM  4.61A  ) 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000305|PubMed:30970244}. Chromosome {ECO:0000305|PubMed:30970244}. Note=Found in actively RNAPolII-transcribed gene bodies. {ECO:0000305|PubMed:30970244}.
Mouse PG classificationNA
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