Gene Information | |
---|---|
Gene Name | KDM1B |
Organism | Homo sapiens (Human) |
Gene Length | 822 |
Protein Names | Lysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B) |
Target Name | lysine-specific histone demethylase 1b |
Target Type | Patented-recorded target |
Gene Age | 645 ( ENSG00000165097 ) |
Evolutionary Stage | Euk+Bac |
AlphaFoldDB | Q8NB78 |
Gene Card | KDM1B |
Uniprot ID | Q8NB78 |
Pfam | PF01593; PF04433; PF07496 |
In ASD | no |
Allosteric Prediction | no (-0.460795864) |
Ortholog in Animals | Alpaca_ KDM1B ( ortholog_one2one ) Dog_ KDM1B ( ortholog_one2one ) GuineaPig_ KDM1B ( ortholog_one2one ) Macaque_ KDM1B ( ortholog_one2one ) Mouse_ Kdm1b ( ortholog_one2one ) Pig_ KDM1B ( ortholog_one2one ) Rat_ Kdm1b ( ortholog_one2one ) Rabbit_ KDM1B ( ortholog_one2one ) |
Ohnologs | NA |
Paralogs | KDM1A, MAOA, SMOX, PPOX, PAOX, MAOB, IL4I1 |
Tissue | NA |
Tissue Specificity | NA |
Pharmacological Animal Models | 0.000730(Chimpanzee);0.018150(Mouse);0.001000(Rat);0.025000(Rabbit) |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 4FWE (X-ray 2.13A ) 4FWF (X-ray 2.70A ) 4FWJ (X-ray 2.90A ) 4GU0 (X-ray 3.10A ) 4GU1 (X-ray 2.94A ) 4GUR (X-ray 2.51A ) 4GUS (X-ray 2.23A ) 4GUT (X-ray 2.00A ) 4GUU (X-ray 2.30A ) 4HSU (X-ray 1.99A ) 6R1U (EM 4.36A ) 6R25 (EM 4.61A ) |
DBSNP | NA |
Subcellular location [CC] | Nucleus {ECO:0000305|PubMed:30970244}. Chromosome {ECO:0000305|PubMed:30970244}. Note=Found in actively RNAPolII-transcribed gene bodies. {ECO:0000305|PubMed:30970244}. |
Mouse PG classification | NA |
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