| Gene Information | |
|---|---|
| Gene Name | KIF5C |
| Organism | Homo sapiens (Human) |
| Gene Length | 957 |
| Protein Names | Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000168280 ) 3 ( ENSG00000276734 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60282 |
| Gene Card | KIF5C |
| Uniprot ID | O60282 |
| Pfam | PF00225 |
| In ASD | no |
| Allosteric Prediction | yes (0.284018693) |
| Ortholog in Animals | Alpaca_ KIF5C ( ortholog_one2one ) Dog_ KIF5C ( ortholog_one2one ) GuineaPig_ KIF5C ( ortholog_one2one ) Macaque_ KIF5C ( ortholog_one2one ) Mouse_ Kif5c ( ortholog_one2one ) Pig_ KIF5C ( ortholog_one2one ) Rat_ Kif5c ( ortholog_one2one ) Rabbit_ KIF5C ( ortholog_one2one ) |
| Ohnologs | KIF5A, KIF5B |
| Paralogs | KIF27, KIF1C, KIF26B, KIF2B, KIF13A, KIFC3, KIFC2, KIF16B, KIF4A, KIF2A, KIF20A, KIF22, KIF3A, KIF13B, KIF5B, KIF1A, KIF3B, KIF3C, KIF1B, CENPE, KIF26A, KIF23, KIF7, KIF5A, KIF18B, KIF25, KIF9, KIF6, KIF14, KIF21B, KIF11, KIF15, KIFC1, KIF12, KIF4B, KIF24, KIF2C, KIF21A, KIF19, KIF17, KIF18A |
| Tissue | cerebral.cortex, brain, testis |
| Tissue Specificity | Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.127407(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs587777570 rs587777035 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000305}. Cell projection, dendrite {ECO:0000269|PubMed:24812067}. Note=Abundant in distal regions of dendrites. {ECO:0000269|PubMed:24812067}. |
| Mouse PG classification | NA |
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