Gene Information
Gene NameSMAGP
OrganismHomo sapiens (Human)
Gene Length97
Protein NamesSmall cell adhesion glycoprotein (Small transmembrane and glycosylated protein)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000170545 )
Evolutionary StageMammalia
AlphaFoldDBQ0VAQ4
Gene CardSMAGP
Uniprot IDQ0VAQ4
PfamNA
In ASDno
Allosteric Predictionno (-1.674912584)
Ortholog in AnimalsAlpaca_ SMAGP ( ortholog_one2one )
GuineaPig_ SMAGP ( ortholog_one2one )
Macaque_ SMAGP ( ortholog_one2one )
Mouse_ Smagp ( ortholog_one2one )
Pig_ SMAGP ( ortholog_one2one )
Rat_ Smagp ( ortholog_one2one )
Rabbit_ SMAGP ( ortholog_one2one )
OhnologsNA
ParalogsTIGIT, NCR3, CD200, NECTIN1, NECTIN2, CADM3, NECTIN4, CADM2, CRTAM, NECTIN3, CADM4, CADM1, CD226, PVR
Tissuecolon
Tissue SpecificityDetected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level). {ECO:0000269|PubMed:15021913}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:15021913};
Single-pass type III membrane protein {ECO:0000255}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:15986429};
Single-pass type III membrane protein {ECO:0000255}. Note=Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions (PubMed:15021913). Detected on cytoplasmic membranes in undifferentiated tumors (PubMed:15986429). {ECO:0000269|PubMed:15021913, ECO:0000269|PubMed:15986429}.
Mouse PG classificationNA
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