| Gene Information | |
|---|---|
| Gene Name | KCNV2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 545 |
| Protein Names | Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000168263 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8TDN2 |
| Gene Card | KCNV2 |
| Uniprot ID | Q8TDN2 |
| Pfam | PF02214; PF00520 |
| In ASD | no |
| Allosteric Prediction | no (-0.273367396) |
| Ortholog in Animals | Alpaca_ KCNV2 ( ortholog_one2one ) Dog_ KCNV2 ( ortholog_one2one ) GuineaPig_ KCNV2 ( ortholog_one2one ) Macaque_ KCNV2 ( ortholog_one2one ) Mouse_ Kcnv2 ( ortholog_one2one ) Pig_ KCNV2 ( ortholog_one2one ) Rat_ Kcnv2 ( ortholog_one2one ) Rabbit_ KCNV2 ( ortholog_one2one ) |
| Ohnologs | KCNG4, KCNS2, KCNV1 |
| Paralogs | KCNS1, KCND1, KCNA7, KCNB2, KCNG3, KCNQ1, KCNQ3, KCNC4, KCNV1, KCNA1, KCNQ4, KCNA10, KCNC3, KCND3, KCNQ2, KCNB1, KCNA6, KCNA2, KCNA5, KCNG1, KCND2, KCNC1, KCNC2, KCNA4, KCNA3, KCNQ5, KCNF1, KCNG2, KCNG4, KCNS3, KCNS2 |
| Tissue | NA |
| Tissue Specificity | Detected in lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary and colon. {ECO:0000269|PubMed:12060745}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs776275880 rs772921412 rs104894116 rs104894115 rs12352254 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1. |
| Mouse PG classification | LPG |
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