| Gene Information | |
|---|---|
| Gene Name | KCNV1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 500 |
| Protein Names | Potassium voltage-gated channel subfamily V member 1 (Neuronal potassium channel alpha subunit HNKA) (Voltage-gated potassium channel subunit Kv8.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164794 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6PIU1 |
| Gene Card | KCNV1 |
| Uniprot ID | Q6PIU1 |
| Pfam | PF02214; PF00520 |
| In ASD | no |
| Allosteric Prediction | no (-0.180396129) |
| Ortholog in Animals | Alpaca_ KCNV1 ( ortholog_one2one ) Dog_ KCNV1 ( ortholog_one2one ) GuineaPig_ KCNV1 ( ortholog_one2one ) Macaque_ KCNV1 ( ortholog_one2one ) Mouse_ Kcnv1 ( ortholog_one2one ) Pig_ KCNV1 ( ortholog_one2one ) Rat_ Kcnv1 ( ortholog_one2one ) Rabbit_ KCNV1 ( ortholog_one2one ) |
| Ohnologs | KCNS1, KCNB1, KCNV2, KCNG4, KCNF1, KCNS3, KCNG3 |
| Paralogs | KCNS1, KCND1, KCNA7, KCNB2, KCNG3, KCNQ1, KCNQ3, KCNC4, KCNA1, KCNQ4, KCNA10, KCNC3, KCNV2, KCND3, KCNQ2, KCNB1, KCNA6, KCNA2, KCNA5, KCNG1, KCND2, KCNC1, KCNC2, KCNA4, KCNA3, KCNQ5, KCNF1, KCNG2, KCNG4, KCNS3, KCNS2 |
| Tissue | brain |
| Tissue Specificity | Detected in brain. {ECO:0000269|PubMed:12383276}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17852611 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:8670833, ECO:0000269|PubMed:9079713}; Multi-pass membrane protein {ECO:0000269|PubMed:8670833, ECO:0000269|PubMed:9079713}. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2. |
| Mouse PG classification | NA |
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