| Gene Information | |
|---|---|
| Gene Name | KCNK9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 374 |
| Protein Names | Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2) |
| Target Name | potassium channel subfamily k member 9 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000169427 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NPC2 |
| Gene Card | KCNK9 |
| Uniprot ID | Q9NPC2 |
| Pfam | PF07885 |
| In ASD | no |
| Allosteric Prediction | yes (0.95176986) |
| Ortholog in Animals | Alpaca_ KCNK9 ( ortholog_one2one ) Dog_ KCNK9 ( ortholog_one2one ) GuineaPig_ KCNK9 ( ortholog_one2one ) Macaque_ KCNK9 ( ortholog_one2one ) Mouse_ Kcnk9 ( ortholog_one2one ) Pig_ KCNK9 ( ortholog_one2one ) Rat_ Kcnk9 ( ortholog_one2one ) Rabbit_ KCNK9 ( ortholog_one2one ) |
| Ohnologs | KCNK15, KCNK3 |
| Paralogs | KCNK6, KCNK15, KCNK3, KCNK13, KCNK1, KCNK17, KCNK2, KCNK18, KCNK16, KCNK12, KCNK7, KCNK4, KCNK5, KCNK10 |
| Tissue | cerebellar.hemisphere, cerebellum |
| Tissue Specificity | Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung. {ECO:0000269|PubMed:11042359, ECO:0000269|PubMed:11431495}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3P1N (X-ray 1.40A ) 3P1O (X-ray 1.90A ) 3P1P (X-ray 1.95A ) 3P1Q (X-ray 1.70A ) 3P1R (X-ray 1.70A ) 3P1S (X-ray 1.65A ) 3SMK (X-ray 2.10A ) 3SML (X-ray 1.90A ) 3SMM (X-ray 2.00A ) 3SMN (X-ray 2.00A ) 3SMO (X-ray 1.80A ) 3SP5 (X-ray 1.80A ) 3SPR (X-ray 1.99A ) 3UX0 (X-ray 1.75A ) 4FR3 (X-ray 1.90A ) 6GHP (X-ray 1.95A ) |
| DBSNP | rs121908332 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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