| Gene Information | |
|---|---|
| Gene Name | KCNJ3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 501 |
| Protein Names | G protein-activated inward rectifier potassium channel 1 (GIRK-1) (Inward rectifier K(+) channel Kir3.1) (Potassium channel, inwardly rectifying subfamily J member 3) |
| Target Name | g protein-activated inward rectifier potassium channel 1 |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000162989 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P48549 |
| Gene Card | KCNJ3 |
| Uniprot ID | P48549 |
| Pfam | PF01007; PF17655 |
| In ASD | no |
| Allosteric Prediction | yes (0.917123686) |
| Ortholog in Animals | Alpaca_ KCNJ3 ( ortholog_one2one ) Dog_ KCNJ3 ( ortholog_one2one ) Macaque_ KCNJ3 ( ortholog_one2one ) Mouse_ Kcnj3 ( ortholog_one2one ) Pig_ KCNJ3 ( ortholog_one2one ) Rat_ Kcnj3 ( ortholog_one2one ) Rabbit_ KCNJ3 ( ortholog_one2one ) |
| Ohnologs | KCNJ2, KCNJ6 |
| Paralogs | KCNJ9, KCNJ5, KCNJ6, KCNJ14, KCNJ18, KCNJ4, KCNJ16, KCNJ12, KCNJ2, KCNJ11, KCNJ15, KCNJ10, KCNJ13, KCNJ8, KCNJ1 |
| Tissue | cerebral.cortex, duodenum, heart, kidney, small.intestine, cerebellum, cerebellar.hemisphere |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs16838016 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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