| Gene Information | |
|---|---|
| Gene Name | KCNJ14 |
| Organism | Homo sapiens (Human) |
| Gene Length | 436 |
| Protein Names | ATP-sensitive inward rectifier potassium channel 14 (Inward rectifier K(+) channel Kir2.4) (IRK-4) (Potassium channel, inwardly rectifying subfamily J member 14) |
| Target Name | atp-sensitive potassium channel |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000182324 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9UNX9 |
| Gene Card | KCNJ14 |
| Uniprot ID | Q9UNX9 |
| Pfam | PF01007; PF17655 |
| In ASD | no |
| Allosteric Prediction | yes (0.318047405) |
| Ortholog in Animals | Alpaca_ KCNJ14 ( ortholog_one2one ) Dog_ KCNJ14 ( ortholog_one2one ) GuineaPig_ KCNJ14 ( ortholog_one2one ) Macaque_ KCNJ14 ( ortholog_one2one ) Mouse_ Kcnj14 ( ortholog_one2one ) Pig_ KCNJ14 ( ortholog_one2one ) Rat_ Kcnj14 ( ortholog_one2one ) Rabbit_ KCNJ14 ( ortholog_one2one ) |
| Ohnologs | KCNJ6, KCNJ4, KCNJ5, KCNJ2, KCNJ12 |
| Paralogs | KCNJ9, KCNJ3, KCNJ5, KCNJ6, KCNJ11, KCNJ15, KCNJ10, KCNJ13, KCNJ8, KCNJ1, KCNJ2, KCNJ18, KCNJ4, KCNJ12, KCNJ16 |
| Tissue | NA |
| Tissue Specificity | Expressed preferentially in retina. {ECO:0000269|PubMed:10942728}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs3745725 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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