| Gene Information | |
|---|---|
| Gene Name | KCNJ12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 433 |
| Protein Names | ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12) |
| Target Name | atp-sensitive inward rectifier potassium channel 12 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000184185 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14500 |
| Gene Card | KCNJ12 |
| Uniprot ID | Q14500 |
| Pfam | PF01007; PF17655; PF08466 |
| In ASD | no |
| Allosteric Prediction | yes (1.037596732) |
| Ortholog in Animals | Dog_ KCNJ12 ( ortholog_one2many ) Mouse_ Kcnj12 ( ortholog_one2many ) Rat_ Kcnj12 ( ortholog_one2many ) |
| Ohnologs | KCNJ4, KCNJ14, KCNJ5, KCNJ2 |
| Paralogs | KCNJ9, KCNJ3, KCNJ5, KCNJ6, KCNJ11, KCNJ15, KCNJ10, KCNJ13, KCNJ8, KCNJ1, KCNJ18, KCNJ4, KCNJ14, KCNJ2, KCNJ16 |
| Tissue | skeletal.muscle, cerebellar.hemisphere, cerebellum |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3752032 rs1657738 rs8076599 rs1657740 rs1714864 rs1657742 rs4985866 rs5021699 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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