| Gene Information | |
|---|---|
| Gene Name | KCNIP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 227 |
| Protein Names | Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000182132 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NZI2 |
| Gene Card | KCNIP1 |
| Uniprot ID | Q9NZI2 |
| Pfam | PF13499; PF13833 |
| In ASD | no |
| Allosteric Prediction | no (-0.483529772) |
| Ortholog in Animals | Alpaca_ KCNIP1 ( ortholog_one2one ) Dog_ KCNIP1 ( ortholog_one2one ) GuineaPig_ KCNIP1 ( ortholog_one2one ) Macaque_ KCNIP1 ( ortholog_one2one ) Mouse_ Kcnip1 ( ortholog_one2one ) Pig_ KCNIP1 ( ortholog_one2one ) Rat_ Kcnip1 ( ortholog_one2one ) Rabbit_ KCNIP1 ( ortholog_one2one ) |
| Ohnologs | KCNIP2, KCNIP3, KCNIP4 |
| Paralogs | KCNIP4, KCNIP2, GUCA1B, VSNL1, HPCAL1, NCS1, KCNIP3, GUCA1C, GUCA1A, RCVRN, CLXN, NCALD, HPCAL4, HPCA |
| Tissue | brain, amygdala, caudate.nucleus, cerebral.cortex, hippocampus, hypothalamus, nucleus.accumbens, putamen, substantia.nigra |
| Tissue Specificity | Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1S1E (X-ray 2.30A ) 2I2R (X-ray 3.35A ) 2NZ0 (X-ray 3.20A ) 7E83 (EM 3.10A ) 7E84 (EM 3.10A ) 7F3F (EM 3.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10676964}; Peripheral membrane protein {ECO:0000305|PubMed:10676964}. Cytoplasm {ECO:0000269|PubMed:10676964}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q8R426}. |
| Mouse PG classification | NA |
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