| Gene Information | |
|---|---|
| Gene Name | KCNH8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1107 |
| Protein Names | Potassium voltage-gated channel subfamily H member 8 (ELK1) (hElk1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (Voltage-gated potassium channel subunit Kv12.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000183960 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96L42 |
| Gene Card | KCNH8 |
| Uniprot ID | Q96L42 |
| Pfam | PF00027; PF00520; PF13426 |
| In ASD | no |
| Allosteric Prediction | yes (0.034429582) |
| Ortholog in Animals | Alpaca_ KCNH8 ( ortholog_one2one ) Dog_ KCNH8 ( ortholog_one2one ) GuineaPig_ KCNH8 ( ortholog_one2one ) Macaque_ KCNH8 ( ortholog_one2one ) Mouse_ Kcnh8 ( ortholog_one2one ) Pig_ KCNH8 ( ortholog_one2one ) Rat_ Kcnh8 ( ortholog_one2one ) Rabbit_ KCNH8 ( ortholog_one2one ) |
| Ohnologs | KCNH2, KCNH4, KCNH3, KCNH6, KCNH7 |
| Paralogs | KCNH7, KCNH1, HCN3, CNGA3, KCNH3, HCN4, HCN2, HCN1, CNGB3, CNGB1, CNGA1, KCNH6, KCNH2, KCNH4, CNGA2, CNGA4, KCNH5 |
| Tissue | pituitary.gland |
| Tissue Specificity | Primarily expressed in the nervous system. {ECO:0000269|PubMed:12890647}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs33915638 rs35160416 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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