| Gene Information | |
|---|---|
| Gene Name | KCNG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 513 |
| Protein Names | Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000026559 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UIX4 |
| Gene Card | KCNG1 |
| Uniprot ID | Q9UIX4 |
| Pfam | PF02214; PF00520 |
| In ASD | no |
| Allosteric Prediction | yes (0.370269031) |
| Ortholog in Animals | Alpaca_ KCNG1 ( ortholog_one2one ) Dog_ KCNG1 ( ortholog_one2one ) GuineaPig_ KCNG1 ( ortholog_one2one ) Macaque_ KCNG1 ( ortholog_one2one ) Mouse_ Kcng1 ( ortholog_one2one ) Pig_ KCNG1 ( ortholog_one2one ) Rat_ Kcng1 ( ortholog_one2one ) |
| Ohnologs | KCNS2, KCNF1, KCNG4, KCNS3, KCNG2, KCNB2 |
| Paralogs | KCNS1, KCND1, KCNA7, KCNB2, KCNG3, KCNQ1, KCNQ3, KCNC4, KCNV1, KCNA1, KCNQ4, KCNA10, KCNC3, KCNV2, KCND3, KCNQ2, KCNB1, KCNA6, KCNA2, KCNA5, KCND2, KCNC1, KCNC2, KCNA4, KCNA3, KCNQ5, KCNF1, KCNG2, KCNG4, KCNS3, KCNS2 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain and placenta, and at much lower levels in kidney and pancreas (PubMed:9434767). {ECO:0000269|PubMed:9434767}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17791052 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19074135}; Multi-pass membrane protein {ECO:0000305}. Note=Colocalizes with KCNB1 at the plasma membrane (PubMed:19074135). {ECO:0000269|PubMed:19074135}. |
| Mouse PG classification | NA |
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