| Gene Information | |
|---|---|
| Gene Name | KCND1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 647 |
| Protein Names | Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) |
| Target Name | voltage-gated potassium channel kv4.1 |
| Target Type | Literature-reported target |
| Gene Age | 382 ( ENSG00000102057 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NSA2 |
| Gene Card | KCND1 |
| Uniprot ID | Q9NSA2 |
| Pfam | PF02214; PF11879; PF00520; PF11601 |
| In ASD | no |
| Allosteric Prediction | no (-0.04843429) |
| Ortholog in Animals | Alpaca_ KCND1 ( ortholog_one2one ) Dog_ KCND1 ( ortholog_one2one ) GuineaPig_ KCND1 ( ortholog_one2one ) Macaque_ KCND1 ( ortholog_one2one ) Mouse_ Kcnd1 ( ortholog_one2one ) Pig_ KCND1 ( ortholog_one2one ) Rat_ Kcnd1 ( ortholog_one2one ) Rabbit_ KCND1 ( ortholog_one2one ) |
| Ohnologs | KCND3, KCND2 |
| Paralogs | KCNS1, KCNA7, KCNB2, KCNG3, KCNQ1, KCNQ3, KCNC4, KCNV1, KCNA1, KCNQ4, KCNA10, KCNC3, KCNV2, KCND3, KCNQ2, KCNB1, KCNA6, KCNA2, KCNA5, KCNG1, KCND2, KCNC1, KCNC2, KCNA4, KCNA3, KCNQ5, KCNF1, KCNG2, KCNG4, KCNS3, KCNS2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus; detected at lower levels in the other parts of the brain. {ECO:0000269|PubMed:10729221}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. Cell projection, dendrite {ECO:0000250}. |
| Mouse PG classification | NA |
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