| Gene Information | |
|---|---|
| Gene Name | KCNA7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 456 |
| Protein Names | Potassium voltage-gated channel subfamily A member 7 (Voltage-gated potassium channel subunit Kv1.7) |
| Target Name | voltage-gated potassium channel kv1.7 |
| Target Type | Literature-reported target |
| Gene Age | 382 ( ENSG00000104848 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q96RP8 |
| Gene Card | KCNA7 |
| Uniprot ID | Q96RP8 |
| Pfam | PF02214; PF00520 |
| In ASD | no |
| Allosteric Prediction | yes (0.177306595) |
| Ortholog in Animals | Alpaca_ KCNA7 ( ortholog_one2one ) Dog_ KCNA7 ( ortholog_one2one ) GuineaPig_ KCNA7 ( ortholog_one2one ) Macaque_ KCNA7 ( ortholog_one2one ) Mouse_ Kcna7 ( ortholog_one2one ) Pig_ KCNA7 ( ortholog_one2one ) Rat_ Kcna7 ( ortholog_one2one ) Rabbit_ KCNA7 ( ortholog_one2one ) |
| Ohnologs | KCNA1, KCNA5, KCNA10, KCNA6, KCNA3, KCNA2, KCNA4 |
| Paralogs | KCNS1, KCND1, KCNB2, KCNG3, KCNQ1, KCNQ3, KCNC4, KCNV1, KCNA1, KCNQ4, KCNA10, KCNC3, KCNV2, KCND3, KCNQ2, KCNB1, KCNA6, KCNA2, KCNA5, KCNG1, KCND2, KCNC1, KCNC2, KCNA4, KCNA3, KCNQ5, KCNF1, KCNG2, KCNG4, KCNS3, KCNS2 |
| Tissue | skeletal.muscle |
| Tissue Specificity | Highly expressed in skeletal muscle, heart and kidney. {ECO:0000269|PubMed:11368907, ECO:0000269|PubMed:11896454}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs1611775 rs1017219 |
| Subcellular location [CC] | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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