| Gene Information | |
|---|---|
| Gene Name | XPR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 696 |
| Protein Names | Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000143324 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBH6 |
| Gene Card | XPR1 |
| Uniprot ID | Q9UBH6 |
| Pfam | PF03124; PF03105 |
| In ASD | no |
| Allosteric Prediction | no (-0.283155331) |
| Ortholog in Animals | Alpaca_ XPR1 ( ortholog_one2one ) Dog_ XPR1 ( ortholog_one2one ) GuineaPig_ XPR1 ( ortholog_one2one ) Macaque_ XPR1 ( ortholog_one2one ) Mouse_ Xpr1 ( ortholog_one2one ) Pig_ XPR1 ( ortholog_one2one ) Rat_ Xpr1 ( ortholog_one2one ) Rabbit_ XPR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle. {ECO:0000269|PubMed:9927670, ECO:0000269|PubMed:9990033}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 5IJH (X-ray 2.43A ) |
| DBSNP | rs786205902 rs786205903 rs786205901 rs786205904 rs1061012 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:23791524}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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