| Gene Information | |
|---|---|
| Gene Name | KBTBD8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 601 |
| Protein Names | Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163376 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NFY9 |
| Gene Card | KBTBD8 |
| Uniprot ID | Q8NFY9 |
| Pfam | PF07707; PF00651; PF01344 |
| In ASD | no |
| Allosteric Prediction | no (-1.000009425) |
| Ortholog in Animals | Alpaca_ KBTBD8 ( ortholog_one2one ) Dog_ KBTBD8 ( ortholog_one2one ) GuineaPig_ KBTBD8 ( ortholog_one2one ) Macaque_ KBTBD8 ( ortholog_one2one ) Mouse_ Kbtbd8 ( ortholog_one2one ) Pig_ KBTBD8 ( ortholog_one2one ) Rat_ Kbtbd8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KLHL40, KLHDC7B, GAN, BACH1, KLHL20, KLHL10, KLHL42, KLHL21, KLHL32, KBTBD7, KBTBD6, BACH2, KLHL30, KLHL15, KLHL38, KLHL41, KLHL26, KLHL17, KBTBD3, KLHL13, KLHL9, KLHL18, KLHL23, KLHDC7A, KLHL31, IVNS1ABP, KLHL1, KEAP1, KLHL8, KLHL2, KLHL29, KBTBD12, KLHL34, KLHL7, KLHL33, KLHL36, KLHL28, KBTBD11, KLHL14, CCIN, BTBD18, IPP, KLHDC8B, KLHL6, KLHL24, KLHL5, KBTBD13, KLHL3, KLHL35, KLHL22, KBTBD2, KLHL12, KLHL4, KLHDC8A |
| Tissue | lymph.node, testis, tonsil |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13096789 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:23578279}. Golgi apparatus {ECO:0000269|PubMed:23578279}. Note=Translocates to the spindle apparatus during mitosis. {ECO:0000269|PubMed:23578279}. |
| Mouse PG classification | NA |
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