| Gene Information | |
|---|---|
| Gene Name | HA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1018 |
| Protein Names | Unconventional myosin-Ig [Cleaved into: Minor histocompatibility antigen HA-2 (mHag HA-2)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | B0I1T2 |
| Gene Card | MYO1G |
| Uniprot ID | B0I1T2 |
| Pfam | PF00063; PF06017 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Specifically expressed in hematopoietic cells. {ECO:0000269|PubMed:11544309, ECO:0000269|PubMed:20071333}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs61739531 rs3735485 rs2107737 rs7792760 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19968988, ECO:0000269|PubMed:20071333}; Peripheral membrane protein {ECO:0000269|PubMed:19968988, ECO:0000269|PubMed:20071333}. Cell projection, phagocytic cup {ECO:0000250|UniProtKB:Q5SUA5}. Note=Recruited to Fc-gamma receptor (Fc-gamma-R) phagocytic cup. In T-cells, transiently accumulates in discrete areas at the plasma membrane of migrating cells or when membranes are deformed (By similarity). Localization at the membrane is not highly dependent on phosphatidylinositol 4,5-bisphosphate levels. Released from the membrane in the presence of ATP. May be enriched in peripheral processes, such as microvilli or ruffles. {ECO:0000250|UniProtKB:Q5SUA5, ECO:0000269|PubMed:20071333}. |
| Mouse PG classification | NA |
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