| Gene Information | |
|---|---|
| Gene Name | ESCO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 601 |
| Protein Names | N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment factor-like protein 2) (EFO2) (EFO2p) (hEFO2) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000171320 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q56NI9 |
| Gene Card | ESCO2 |
| Uniprot ID | Q56NI9 |
| Pfam | PF13880; PF13878 |
| In ASD | no |
| Allosteric Prediction | no (-0.380889636) |
| Ortholog in Animals | Alpaca_ ESCO2 ( ortholog_one2one ) Dog_ ESCO2 ( ortholog_one2one ) GuineaPig_ ESCO2 ( ortholog_one2one ) Macaque_ ESCO2 ( ortholog_one2one ) Mouse_ Esco2 ( ortholog_one2one ) Rat_ Esco2 ( ortholog_one2many ) Rat_ AABR07057438.1 ( ortholog_one2many ) Rat_ AC110315.1 ( ortholog_one2many ) Rabbit_ ESCO2 ( ortholog_one2one ) |
| Ohnologs | ESCO1 |
| Paralogs | REV1, POLI, ESCO1, POLH, POLK |
| Tissue | NA |
| Tissue Specificity | Widely expressed in fetal tissues. In adult, it is expressed in thymus, placenta and small intestine. {ECO:0000269|PubMed:15821733}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4732748 rs57479434 rs80359868 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15958495, ECO:0000269|PubMed:19907496}. Chromosome {ECO:0000269|PubMed:15958495, ECO:0000269|PubMed:19907496}. Note=Nuclear in interphase cells, excluded from chromosomes during metaphase but reassociates with chromosomes in telophase. {ECO:0000269|PubMed:15958495}. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |