| Gene Information | |
|---|---|
| Gene Name | METTL15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 407 |
| Protein Names | 12S rRNA N4-methylcytidine (m4C) methyltransferase (12S rRNA m4C methyltransferase) (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1) (Methyltransferase-like protein 15) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000169519 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | A6NJ78 |
| Gene Card | METTL15 |
| Uniprot ID | A6NJ78 |
| Pfam | PF01795 |
| In ASD | no |
| Allosteric Prediction | no (-1.735663633) |
| Ortholog in Animals | Alpaca_ METTL15 ( ortholog_one2one ) Dog_ METTL15 ( ortholog_one2one ) GuineaPig_ METTL15 ( ortholog_one2one ) Macaque_ METTL15 ( ortholog_one2one ) Mouse_ Mettl15 ( ortholog_one2one ) Pig_ METTL15 ( ortholog_one2one ) Rat_ Mettl15 ( ortholog_one2one ) Rabbit_ METTL15 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.008790(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7PNX (EM 2.76A ) 7PNY (EM 3.06A ) 7PNZ (EM 3.09A ) |
| DBSNP | rs2883478 rs11823114 rs11030280 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:31665743, ECO:0000269|PubMed:32371392}. |
| Mouse PG classification | NA |
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