| Gene Information | |
|---|---|
| Gene Name | KAT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 425 |
| Protein Names | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Glycine transaminase AADAT) (EC 2.6.1.4) (Kynurenine aminotransferase II) (Kynurenine--glyoxylate transaminase AADAT) (EC 2.6.1.63) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II) (Methionine--glyoxylate transaminase AADAT) (EC 2.6.1.73) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8N5Z0 |
| Gene Card | AADAT |
| Uniprot ID | Q8N5Z0 |
| Pfam | PF00155 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2QLR (X-ray 2.30A ) 2R2N (X-ray 1.95A ) 2VGZ (X-ray 2.30A ) 2XH1 (X-ray 2.10A ) 3DC1 (X-ray 2.50A ) 3UE8 (X-ray 3.22A ) 4GDY (X-ray 2.89A ) 4GE4 (X-ray 2.41A ) 4GE7 (X-ray 2.10A ) 4GE9 (X-ray 2.43A ) 4GEB (X-ray 2.15A ) 5EFS (X-ray 1.83A ) 5EUN (X-ray 1.82A ) 5TF5 (X-ray 1.81A ) 6D0A (X-ray 1.47A ) 6T8P (X-ray 2.02A ) 6T8Q (X-ray 2.51A ) |
| DBSNP | rs56350236 |
| Subcellular location [CC] | Mitochondrion {ECO:0000305}. |
| Mouse PG classification | NA |
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