| Gene Information | |
|---|---|
| Gene Name | TESK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 571 |
| Protein Names | Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2) |
| Target Name | testis-specific kinase 2 |
| Target Type | Literature-reported target |
| Gene Age | 544 ( ENSG00000070759 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96S53 |
| Gene Card | TESK2 |
| Uniprot ID | Q96S53 |
| Pfam | PF07714 |
| In ASD | no |
| Allosteric Prediction | no (-0.315456085) |
| Ortholog in Animals | Alpaca_ TESK2 ( ortholog_one2one ) Dog_ MUTYH ( ortholog_one2one ) GuineaPig_ TESK2 ( ortholog_one2one ) Macaque_ TESK2 ( ortholog_one2one ) Mouse_ Tesk2 ( ortholog_one2one ) Pig_ TESK2 ( ortholog_one2one ) Rat_ Tesk2 ( ortholog_one2one ) Rabbit_ TESK2 ( ortholog_one2one ) |
| Ohnologs | TESK1 |
| Paralogs | LIMK2, RIPK1, LRRK2, TNNI3K, KSR2, MAP3K10, RIPK2, MOS, MAP3K9, MLKL, MAP3K20, ARAF, TESK1, MAP3K13, BRAF, ILK, MAP3K11, RAF1, MAP3K12, MAP3K21, LIMK1, KSR1, RIPK3 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in testis and prostate. Found predominantly in non-germinal Sertoli cells. {ECO:0000269|PubMed:10512679, ECO:0000269|PubMed:11418599}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1428512439 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11418599}. |
| Mouse PG classification | NA |
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