Gene Information
Gene NameISG58
OrganismHomo sapiens (Human)
Gene Length482
Protein NamesInterferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Interferon-induced 58 kDa protein) (Retinoic acid- and interferon-inducible 58 kDa protein) (P58)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ13325
Gene CardIFIT5
Uniprot IDQ13325
PfamPF07719; PF13181
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3ZGQ  (X-ray  2.20A  4HOQ  (X-ray  2.07A  4HOR  (X-ray  1.86A  4HOS  (X-ray  2.00A  4HOT  (X-ray  2.50A  4J0U  (X-ray  1.97A 
DBSNP NA 
Subcellular location [CC]Cell projection, ruffle membrane {ECO:0000269|PubMed:23317505}. Note=Colocalized with RIGI at cell surface ruffles. Localizes to actin-rich protrusions from the apical cell surface.
Mouse PG classificationNA
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