| Gene Information | |
|---|---|
| Gene Name | TGFBRAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 860 |
| Protein Names | Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000135966 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WUH2 |
| Gene Card | TGFBRAP1 |
| Uniprot ID | Q8WUH2 |
| Pfam | PF00637; PF00780; PF10366; PF10367 |
| In ASD | no |
| Allosteric Prediction | no (-0.999600612) |
| Ortholog in Animals | Alpaca_ TGFBRAP1 ( ortholog_one2one ) Dog_ TGFBRAP1 ( ortholog_one2one ) GuineaPig_ TGFBRAP1 ( ortholog_one2one ) Macaque_ TGFBRAP1 ( ortholog_one2one ) Mouse_ Tgfbrap1 ( ortholog_one2one ) Pig_ TGFBRAP1 ( ortholog_one2one ) Rat_ Tgfbrap1 ( ortholog_one2one ) Rabbit_ TGFBRAP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | VPS39 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.152946(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2241797 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11278302}. Early endosome {ECO:0000269|PubMed:25266290}. Note=Colocalizes with TGF-beta receptors in the absence of signaling. |
| Mouse PG classification | NA |
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