| Gene Information | |
|---|---|
| Gene Name | CUEDC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 287 |
| Protein Names | CUE domain-containing protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000107874 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H467 |
| Gene Card | CUEDC2 |
| Uniprot ID | Q9H467 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.000340804) |
| Ortholog in Animals | Alpaca_ CUEDC2 ( ortholog_one2one ) Dog_ CUEDC2 ( ortholog_one2one ) GuineaPig_ CUEDC2 ( ortholog_one2one ) Mouse_ Cuedc2 ( ortholog_one2one ) Pig_ CUEDC2 ( ortholog_one2one ) Rat_ Cuedc2 ( ortholog_one2one ) Rabbit_ CUEDC2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Significantly up-regulated in breast tumor tissues compared with matched adjacent normal tissues (at protein level). Levels inversely correlate with ESR1 in breast cancers and are lower in low-grade tumors compared to high-grade tumors. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17347654}. Nucleus {ECO:0000269|PubMed:17347654}. |
| Mouse PG classification | NA |
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