| Gene Information | |
|---|---|
| Gene Name | CASP8AP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1982 |
| Protein Names | CASP8-associated protein 2 (FLICE-associated huge protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000118412 ) 3 ( ENSG00000288475 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UKL3 |
| Gene Card | CASP8AP2 |
| Uniprot ID | Q9UKL3 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.161884701) |
| Ortholog in Animals | Alpaca_ CASP8AP2 ( ortholog_one2one ) Dog_ CASP8AP2 ( ortholog_one2one ) GuineaPig_ CASP8AP2 ( ortholog_one2one ) Macaque_ CASP8AP2 ( ortholog_one2one ) Mouse_ Casp8ap2 ( ortholog_one2one ) Pig_ CASP8AP2 ( ortholog_one2one ) Rat_ Casp8ap2 ( ortholog_one2one ) Rabbit_ CASP8AP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LR8 (NMR - ) 6ANO (X-ray 2.61A ) 6AOZ (X-ray 2.10A ) 6AP0 (X-ray 2.58A ) |
| DBSNP | rs3799896 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Nucleus, PML body. Mitochondrion. Note=Exported from the nucleus to the mitochondria upon FAS activation. |
| Mouse PG classification | NA |
| click here to return to the previous page | |