| Gene Information | |
|---|---|
| Gene Name | POP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 45 |
| Protein Names | NLR family pyrin domain-containing protein 2B (Pyrin domain-containing protein 2-like protein POP4) (Pyrin-only protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000105171 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P0DMW2 |
| Gene Card | NLRP2B |
| Uniprot ID | P0DMW2 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.434378555) |
| Ortholog in Animals | Alpaca_ POP4 ( ortholog_one2one ) Dog_ POP4 ( ortholog_one2one ) GuineaPig_ POP4 ( ortholog_one2one ) Macaque_ POP4 ( ortholog_one2one ) Mouse_ Pop4 ( ortholog_one2one ) Pig_ POP4 ( ortholog_one2one ) Rat_ Pop4 ( ortholog_one2one ) Rabbit_ POP4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues tested, including spleen, lymph node, thymus, tonsil, peripheral blood leukocyte, bone marrow, liver, heart, brain, placenta, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:24871464}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:24871464}. Nucleus {ECO:0000269|PubMed:24871464}. Note=Targeted to the nucleus upon TNF-alpha treatment. {ECO:0000269|PubMed:24871464}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |