| Gene Information | |
|---|---|
| Gene Name | KAB |
| Organism | Homo sapiens (Human) |
| Gene Length | 1584 |
| Protein Names | Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q5SW79 |
| Gene Card | CEP170 |
| Uniprot ID | Q5SW79 |
| Pfam | PF15308; PF00498 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4JON (X-ray 2.15A ) |
| DBSNP | rs2631092 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:30354798, ECO:0000269|PubMed:31789463}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:15616186, ECO:0000269|PubMed:23386061, ECO:0000269|PubMed:31789463}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:15616186}. Note=Associated with the mature mother centriole. Associated with spindle microtubules during mitosis. Localizes to the distal appendage region of the centriole (PubMed:31789463). Localizes at the centriole proximal ends (PubMed:31789463). {ECO:0000269|PubMed:23386061, ECO:0000269|PubMed:31789463}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |