| Gene Information | |
|---|---|
| Gene Name | K6HF |
| Organism | Homo sapiens (Human) |
| Gene Length | 551 |
| Protein Names | Keratin, type II cytoskeletal 75 (Cytokeratin-75) (CK-75) (Keratin-6 hair follicle) (hK6hf) (Keratin-75) (K75) (Type II keratin-K6hf) (Type-II keratin Kb18) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95678 |
| Gene Card | KRT75 |
| Uniprot ID | O95678 |
| Pfam | PF00038; PF16208 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in hair follicles from scalp. Specifically expressed in the of the hair companion layer follicle, a single layered band of flat and vertically oriented cells between the cuboidal outer root sheath (ORS) cells and the inner root sheath (IRS) that stretches from the lowermost bulb region to the isthmus of the follicle. Also expressed in medullated hairs. In nails, it is almost exclusively present in the nail bed (at protein level). {ECO:0000269|PubMed:14675170, ECO:0000269|PubMed:15292489, ECO:0000269|PubMed:18032949, ECO:0000269|PubMed:9856802}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2232384 rs298109 rs2232386 rs2232387 rs2232390 rs2232393 rs2232398 rs2232402 rs2232405 rs2232406 rs298104 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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