Gene Information
Gene NameK12
OrganismHomo sapiens (Human)
Gene Length248
Protein NamesSecreted and transmembrane protein 1 (Protein K-12)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8WVN6
Gene CardSECTM1
Uniprot IDQ8WVN6
PfamNA
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityDetected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts. {ECO:0000269|PubMed:15742156, ECO:0000269|PubMed:9480746}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}. Secreted.
Mouse PG classificationNA
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