| Gene Information | |
|---|---|
| Gene Name | FEZ1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 392 |
| Protein Names | Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000149557 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99689 |
| Gene Card | FEZ1 |
| Uniprot ID | Q99689 |
| Pfam | PF07763 |
| In ASD | no |
| Allosteric Prediction | no (-0.59481497) |
| Ortholog in Animals | Alpaca_ FEZ1 ( ortholog_one2one ) Dog_ FEZ1 ( ortholog_one2one ) GuineaPig_ FEZ1 ( ortholog_one2one ) Macaque_ FEZ1 ( ortholog_one2one ) Mouse_ Fez1 ( ortholog_one2one ) Pig_ FEZ1 ( ortholog_one2one ) Rat_ Fez1 ( ortholog_one2one ) Rabbit_ FEZ1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FEZ2 |
| Tissue | NA |
| Tissue Specificity | Mainly expressed in brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs597570 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18439996}. Cell membrane {ECO:0000250}. Note=Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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